It is understood there have been a number of fatalities at a fire at a domestic residence in Waterford City.
Gardaí and other emergency services are at the scene.
A spokesperson said: “As this is an ongoing evolving incident An Garda Síochána is not in a position to provide any further detail.”
Taoiseach Micheál Martin has described it as a “deeply disturbing situation”.
Mr Martin said details of the incident are still unfolding
Speaking ahead of a cabinet meeting in Dublin, he said: “Our thoughts and prayers are with anybody who has lost their lives and all who are affected.
“We thank the first responders who are at the scene.
“We say to everyone to give space to the first responders, to the Gardaí to deal with what clearly is a very worrying and deeply disturbing situation.”
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